We provide here a list of known ototoxic drugs and herbs that have been known to cause or exacerbate tinnitus. This list is for educational purposes only and is available as a resource to you to use in your discussions with your health care professional. We thank doctor Neil Bauman, Ph.D., for his expertise in this area and for compiling this list for us.
A wealth of research has gone into understanding the mechanisms of tinnitus due to the increased concern in our ageing and noise exposed society through the support of organizations such as the Tinnitus Research Institute, the American Tinnitus Association and even the US Department of Defense. This research has helped us to understand not only why and how this phantom percept can develop, but also sheds light on why it may sound like a hiss for one person and a high pitched tone for another.7 In addition, neuroscientists have shown connections between the limbic system (where emotions are processed) and the auditory system; it is not uncommon for tinnitus to increase during times of stress or negative emotions.5 As such, the effective tinnitus treatment strategies should be enjoyable and positive, and should account for the variability in what tinnitus sounds like for each patient.
Most people with tinnitus also have hearing loss. Hence, hearing aids can be an effective part of any sound therapy.  Hearing aids alone can provide partial or total relief from tinnitus. If you’re experiencing challenges with your hearing as well as tinnitus, a combination of a hearing solution with built-in sound generators can often be prescribed. You can expect improved levels of hearing which also helps to minimise the effects of the condition in the same way that sound therapy might.
Some people experience a sound that beats in time with their pulse, known as pulsatile tinnitus or vascular tinnitus.[40] Pulsatile tinnitus is usually objective in nature, resulting from altered blood flow, increased blood turbulence near the ear, such as from atherosclerosis or venous hum,[41] but it can also arise as a subjective phenomenon from an increased awareness of blood flow in the ear.[40] Rarely, pulsatile tinnitus may be a symptom of potentially life-threatening conditions such as carotid artery aneurysm[42] or carotid artery dissection.[43] Pulsatile tinnitus may also indicate vasculitis, or more specifically, giant cell arteritis. Pulsatile tinnitus may also be an indication of idiopathic intracranial hypertension.[44] Pulsatile tinnitus can be a symptom of intracranial vascular abnormalities and should be evaluated for irregular noises of blood flow (bruits).[45]

Assessment of psychological processes related to tinnitus involves measurement of tinnitus severity and distress (i.e., nature and extent of tinnitus-related problems), measured subjectively by validated self-report tinnitus questionnaires.[18] These questionnaires measure the degree of psychological distress and handicap associated with tinnitus, including effects on hearing, lifestyle, health and emotional functioning.[62][63][64] A broader assessment of general functioning, such as levels of anxiety, depression, stress, life stressors and sleep difficulties, is also important in the assessment of tinnitus due to higher risk of negative well-being across these areas, which may be affected by or exacerbate the tinnitus symptoms for the individual.[65] Overall, current assessment measures are aimed to identify individual levels of distress and interference, coping responses and perceptions of tinnitus in order to inform treatment and monitor progress. However, wide variability, inconsistencies and lack of consensus regarding assessment methodology are evidenced in the literature, limiting comparison of treatment effectiveness.[66] Developed to guide diagnosis or classify severity, most tinnitus questionnaires have been shown to be treatment-sensitive outcome measures.[67]
We provide here a list of known ototoxic drugs and herbs that have been known to cause or exacerbate tinnitus. This list is for educational purposes only and is available as a resource to you to use in your discussions with your health care professional. We thank doctor Neil Bauman, Ph.D., for his expertise in this area and for compiling this list for us.
Hair cells can be damaged by exposure to loud noise, which could lead to tinnitus. This can occur gradually as a result of exposure to noises over prolonged periods or may be caused by exposure to louder noises over a shorter period of time. If you are exposed to loud noises, you should always wear ear protection. Find out more about the subject on our How Loud Is Loud article and see if your job or lifestyle could be putting your ears at risk,
When tinnitus is unexpected and unwelcomed, it can lead to a negative reaction to the tinnitus. This can create a vicious cycle. When tinnitus is perceived, it can prompt emotions, including frustration, fear, unhappiness, etc.  These can, in turn, cause physical reactions such as anxiety and stress.  This reinforces the tinnitus and perpetuates the cycle. 
Tinnitus also could be the result of neural circuits thrown out of balance when damage in the inner ear changes signaling activity in the auditory cortex, the part of the brain that processes sound. Or it could be the result of abnormal interactions between neural circuits. The neural circuits involved in hearing aren’t solely dedicated to processing sound. They also communicate with other parts of the brain, such as the limbic region, which regulates mood and emotion.
The noise heard by people with tinnitus may be a buzzing, ringing, roaring, whistling, or hissing sound and is often associated with hearing loss. Some people hear more complex sounds that may be different at different times. These sounds are more noticeable in a quiet environment and when people are not concentrating on something else. Thus, tinnitus tends to be most disturbing to people when they are trying to sleep. However, the experience of tinnitus is highly individual. Some people are very disturbed by their symptoms, whereas others find them quite bearable.

Tinnitus is when people think they hear something in their ears but there is actually no sound. People with tinnitus actually do "hear" noises that range from a whistle to a crackling noise to a roar. It can happen only occasionally, can occur for a period of days then take a break before recurring again, or it can be constant. The sound can vary in pitch from quiet to unbearably loud, or it can stay the same.


Some patients choose to get involved in “tinnitus retraining,” which involves wearing a device in the ears that provides soothing music or noise, along with undergoing counseling. The goal is to help your body and brain learn to get accustomed to tinnitus noise, which reduces your negative reactions to unwanted sounds. Support and counseling during the process can be helpful for reducing anxiety. Researchers are now learning more about the benefits of coherent cognitive behavioral therapy interventions to help treat distress associated with tinnitus. (3)
Dr. Julie Prutsman’s team of audiologists offer a higher standard of expertise. She has been deeply involved with tinnitus for more than 15 years, long before effective treatments had been developed beyond hearing aids and maskers. Dr. Julie also studied under one of the industry’s most respected and leading medical experts, Dr. Pawel Jastreboff, and she has personally trained each and every one of her doctors.
According to the American Tinnitus Association, most cases of tinnitus are caused by hearing loss. Occasionally though, tinnitus is caused by an irritation to the auditory system. Tinnitus can sometimes be a symptom of a problem with the temporomandibular joint (TMJ). If your tinnitus is caused by TMJ, then a dental procedure or realignment of your bite may alleviate the problem.
Tinnitus is the perception of sound when no actual external noise or sound is present. It is often referred to as “ringing” in the ears. I have even heard some people call it “head noises.” While ringing sounds are very common, many people will describe the sound they hear as buzzing, hissing, whistling, swooshing, and clicking. In some rare cases, tinnitus patients report hearing music. I hear about 2,000 crickets all going at once! 
We provide here a list of known ototoxic drugs and herbs that have been known to cause or exacerbate tinnitus. This list is for educational purposes only and is available as a resource to you to use in your discussions with your health care professional. We thank doctor Neil Bauman, Ph.D., for his expertise in this area and for compiling this list for us.
Can an iPhone app truly relieve tinnitus? Believe it or not, the answer is yes. The ReSound LiNX2 app utilizes a combination of sound therapy and relaxation exercises to reduce the severity of tinnitus. The convenient app can be used in combination with hearing instruments, which are small but strong. This groundbreaking program transforms your iPhone into a remote control for your hearing aid.
Some persons with severe TMJ (temporomandibular joint) arthritis have severe tinnitus. Generally these persons say that there is a "screeching" sound. This is another somatic tinnitus. TMJ is extremely common -- about 25% of the population. The exact prevalence of TMJ associated tinnitus is not established, but presumably it is rather high too. Having TMJ increases the odds that you have tinnitus too, by about a factor of 1.6-3.22 (Park and Moon, 2014; Lee et al, 2016). This is the a large risk factor for tinnitus, similar to the risk from hearing loss (see table above).
Diseases, illnesses and injuries. There are several medical conditions that can cause tinnitus. These include Meniere’s disease, temporomandibular joint disorders (TMJ), head or neck injuries, brain tumors, etc. Most people don’t know if they have Meniere’s disease until properly diagnosed. This RARE disease brings on dizziness, tinnitus and ear pressure that can last for a short period of time and then disappears. TMJ causes pain in your jaw muscles. With TMJ, you’ll often hear a clicking noise when chewing. TMJ has shown to influence your chances of developing tinnitus, so be sure to treat the condition in order to reduce your chances of getting tinnitus. Head and neck injuries have also been shown to cause tinnitus, so always wear your helmet when you’re out biking and drive safely when you’re in your car.Believe it or not, but tinnitus can be caused by something as simple as an ear infection. Don’t take ear infections lightly they can be devastating at any age. Brain tumors, while equally as rare as Meniere’s disease, can also generate tinnitus symptoms. While you can alleviate your tinnitus immediately with an over the counter tinnitus treatment, you should also seek the help of a tinnitus specialist in your area to determine what the underlying cause of your tinnitus is.
Information on this website is provided for informational purposes only and is not intended as a substitute for the advice provided by your physician or other healthcare professional. You should not use the information on this website for diagnosing or treating a health problem or disease, or prescribing any medication or other treatment. Any third party offering or advertising on this website does not constitute an endorsement by Andrew Weil, M.D. or Healthy Lifestyle Brands.
Once the music package (MP3 player preloaded with assigned music tracks and headphones) was ready, participants were briefed on safe listening levels, and were instructed to complete a weekly log book to record their listening duration and frequency. The algorithms which modified the music provided to participants are built into proprietary software that was developed internally by Sound Options Tinnitus Treatments Inc. The modified and placebo music packages consisted of 4 hours of classical music.
Dr. Julie Prutsman’s team of audiologists offer a higher standard of expertise. She has been deeply involved with tinnitus for more than 15 years, long before effective treatments had been developed beyond hearing aids and maskers. Dr. Julie also studied under one of the industry’s most respected and leading medical experts, Dr. Pawel Jastreboff, and she has personally trained each and every one of her doctors.
Wearable sound generators are small electronic devices that fit in the ear and use a soft, pleasant sound to help mask the tinnitus. Some people want the masking sound to totally cover up their tinnitus, but most prefer a masking level that is just a bit louder than their tinnitus. The masking sound can be a soft “shhhhhhhhhhh,” random tones, or music.
Though the exact cause of tinnitus — as in the specific mechanism that creates these phantom sounds in some people — remains unknown, contributing factors and triggers have been identified. Excessive exposure to loud noise is often a factor because of the damage done to your auditory system. Tinnitus may also result from jaw-joint dysfunction (e.g., teeth grinding, temporomandibular joint disorder) or chronic neck muscle strain.
Sound waves travel through the ear canal to the middle and inner ear, where hair cells in part of the cochlea help transform sound waves into electrical signals that then travel to the brain's auditory cortex via the auditory nerve. When hair cells are damaged — by loud noise or ototoxic drugs, for example — the circuits in the brain don't receive the signals they're expecting. This stimulates abnormal activity in the neurons, which results in the illusion of sound, or tinnitus.
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