Like Shore and Kilgard’s work, most of the promising research on tinnitus has to do with stimulating or altering the brain’s hyperactivity in ways that reduce tinnitus. Some studies have shown electromagnetic brain stimulation — using either invasive or noninvasive techniques, including procedures that involve surgically implanted electrodes or scalp electrodes — may help reverse a patient’s tinnitus. (6) While none of these treatment options are currently available, all have shown some success in treating the condition.
As an initial test of our treatment, we first conducted a small pilot study to see if there were measurable benefits within 3 to 6 months of using this therapy. While we did not inform participants of whether they would receive a treatment or unaltered music, every participant in fact received a treatment. Participants reported a drop in scores on the Tinnitus Handicap Inventory (THI) within 3 months of using their personalized sound therapy for about 2 hours a day. THI is a psychometrically robust and validated questionnaire that assesses the impact of tinnitus on daily living and the degree of distress suffered by the tinnitus patient. Furthermore, we saw increased benefits after 6 months of treatment use (Figure 1). This data suggested that our treatment may be engaging brain plasticity in a positive manner, thereby gradually reducing tinnitus over time. Armed with this information, we designed a more rigorous trial that is very uncommon among research in tinnitus therapies.
Tinnitus is usually described as a ringing in the ears, but it can also sound like clicking, hissing, roaring, or buzzing. Tinnitus involves perceiving sound when no external noise is present. The sound can be very soft or very loud, and high-pitched or low-pitched. Some people hear it in one ear and others hear it in both. People with severe tinnitus may have problems hearing, working, or sleeping.
Pulsatile tinnitus is generally caused by abnormalities or disorders affecting the blood vessels (vascular disorders), especially the blood vessels near or around the ears. Such abnormalities or disorders can cause a change in the blood flow through the affected blood vessels. The blood vessels could be weakened from damage caused by hardening of the arteries (atherosclerosis). For example, abnormalities affecting the carotid artery, the main artery serving the brain, can be associated with pulsatile tinnitus. A rare cause of pulsatile tinnitus is a disorder known as fibromuscular dysplasia (FMD), a condition characterized by abnormal development of the arterial wall. When the carotid artery is affected by FMD, pulsatile tinnitus can develop.
Individuals were recruited from within and around Hamilton, Ontario via online announcements and audiology clinics. Applicants were initially interviewed via telephone to screen for all inclusion and exclusion criteria for the study in order to determine whether they qualified for on-site screening. The on-site screening, and characterization of participants’ hearing thresholds and tinnitus profiles were conducted in a lab at McMaster University using a computer-based tinnitus assessment tool. Participants were randomly allocated to the treatment or placebo-control group. The assignment of the treatment or placebo music package was completed by a distributor site independent of the research study site. Participants and research personnel were blinded to which music package the participants received.
About six percent of the general population has what they consider to be "severe" tinnitus. That is a gigantic number of people ! Tinnitus is more common with advancing age. In a large study of more than 2000 adults aged 50 and above, 30.3% reported having experienced tinnitus, with 48% reporting symptoms in both ears. Tinnitus had been present for at least 6 years in 50% of cases, and most (55%) reported a gradual onset. Tinnitus was described as mildly to extremely annoying by 67%.(Sindhusake et al. 2003)