On the internet, on TV and radio commercials and in papers and magazines you can easily find many who offers a method that can cure, or at least reduce, tinnitus. This could for example be in the form of “medication” (pills and injections), herbal treatments, different types of therapy and hypnosis. But other “cures” also exist. The list of “cures” is long, and is getting longer.
We provide here a list of known ototoxic drugs and herbs that have been known to cause or exacerbate tinnitus. This list is for educational purposes only and is available as a resource to you to use in your discussions with your health care professional. We thank doctor Neil Bauman, Ph.D., for his expertise in this area and for compiling this list for us.
Somatic tinnitus is caused, worsened, or otherwise related to your body’s own sensory system. Sensory signals coming from various parts of the body are disrupted, causing a spasm that produces tinnitus. Those who have somatic tinnitus usually have it in only one ear. Depending on the root cause your doctor may come up with treatment options to alleviate the symptoms.
 Sound therapy can be effective in treating tinnitus because it may make the tinnitus less noticeable or mask the tinnitus or fade tinnitus. Hearing aids are included as a critical component of a sound therapy program. Modern hearing aids come with a special tinnitus managing sounds along with digital amplification. They are much evolved over the older technology. Different products work in different ways, although most hearing aids can alleviate tinnitus, certain hearing aids have built-in technology specifically for tinnitus relief. At amplifon, we have a clearly defined way to measure and quantify chronic tinnitus. As per the severity of the problem, an appropriate combination of treatment methods is selected to deal with your tinnitus. Amplifon audiologists are specially trained in counselling procedures as well which is another critical element of sound therapy. Consult your Amplifon audiologist to find more details about what suits you to deal with your tinnitus problem.
There are many different conditions and disorders that affect nerve channels leading to the ears, which can cause someone to hear abnormal ringing or other sounds in their ears. These conditions usually cause other symptoms at the same time (such as dizziness, hearing loss, headaches, facial paralysis, nausea and loss of balance), which doctors use as clues to uncover the underlying cause of tinnitus.
Tinnitus remains a symptom that affects the lives of millions of people. Research is directed not only at its treatment, but also at understanding why it occurs. Research by doctors at the University at Buffalo, The State University of New York, Dalhousie University (Canada), and Southeast China University have published research using electrophysiology and functional MRI to better understand what parts of the brain are involved in hearing and the production of tinnitus. Their research has found that much larger areas of the brain are involved with the process of hearing than previously believed, which may help direct future diagnostic and therapeutic options.
Ototoxic drugs can also cause subjective tinnitus, as they may cause hearing loss, or increase the damage done by exposure to loud noise. Those damages can occur even at doses that are not considered ototoxic.[30] Over 260 medications have been reported to cause tinnitus as a side effect.[31] In many cases, however, no underlying cause could be identified.[2]
FACT: Some companies will try to point you to a miraculous tinnitus cure where a few pills will stop all signs of tinnitus. While much research has been done around the effects of medication and vitamin supplements on tinnitus, there is currently no proven tinnitus cure.  Only tinnitus management devices and sound therapy have been proven to decrease the effects of tinnitus.
Most people with tinnitus also have hearing loss. Hence, hearing aids can be an effective part of any sound therapy.  Hearing aids alone can provide partial or total relief from tinnitus. If you’re experiencing challenges with your hearing as well as tinnitus, a combination of a hearing solution with built-in sound generators can often be prescribed. You can expect improved levels of hearing which also helps to minimise the effects of the condition in the same way that sound therapy might.
Lidocaine, a medication used for the treatment of certain types of abnormal heart rhythms, has been shown to relieve tinnitus for some people, but it must be given intravenously or into the middle ear to be effective. However, the benefits of lidocaine are almost always outweighed by the risks of the drug and it is therefore not recommended and not used for tinnitus.
Every person living with tinnitus hears a unique sound. The sound can be a low or high frequency, and its volume and pitch may change over time, with the severity varying from person to person. Those with acute tinnitus may struggle to sleep, focus at work, or communicate with others. In such cases, treatment plays a crucial role in helping an individual regain control of his or her life.
Research shows a frequent correlation between tinnitus and hearing loss. Because tinnitus is perceived differently by each sufferer, an exact diagnosis is essential. A doctor may conduct ENT, dental, orthodontic, and orthopedic examinations in order to establish whether a case can be medically treated or not. The pitch and volume of tinnitus can be determined by special diagnostic test, and a hearing test can reveal whether hearing loss is also involved. Treatment with hearing aids is often the first step to relief from tinnitus. Hearing aids compensate for hearing loss, which enables concentration on external sounds instead of internal noises.
Tinnitus is commonly described as a ringing in the ears, but it also can sound like roaring, clicking, hissing, or buzzing. It may be soft or loud, high pitched or low pitched. You might hear it in either one or both ears. Roughly 10 percent of the adult population of the United States has experienced tinnitus lasting at least five minutes in the past year. This amounts to nearly 25 million Americans.

Many of us experience tinnitus every once in a while. If you’re exposed to extremely loud noise, or leave a noisy environment for a quiet one, you may notice a temporary buzzing or ringing in your ear. Maybe you’ve been near loud construction—like a jackhammer, or stepped out of a loud action movie or music concert to a quiet lobby or street. (Be aware: even a single exposure to very loud noise can do damage to your hearing, and increase your risk for tinnitus.)

Physical exam: Physical examination will focus on the head and neck, and especially the ears, including the auditory canals and tympanic membranes. Since the sense of hearing is conducted through one of the cranial nerves (the short nerves that lead directly from the brain to the face, head and neck), a careful neurologic exam also may be performed. Weakness or numbness in the face, mouth, and neck may be associated with a tumor or other structural abnormality pressing on a nerve. The healthcare professional may listen to the flow in the carotid arteries in the neck for an abnormal sound (bruit), since carotid artery stenosis (narrowing of the artery) can transmit a sound to the ear that may cause tinnitus.
Demographic variables (age, sex, type of tinnitus) and baseline THI scores of placebo (n = 16) and treatment (n = 11) groups did not significantly differ from one another at the start of the study. At 3 months, participants in the treatment group reported significantly lower scores on the THI when compared to the placebo group (p < .05). The treatment group also showed an 11-point drop in THI scores when comparing baseline and 3 months (p < .05; please see Figure 2). THI scores for the placebo group comparing both time points were non-significant. Past studies have indicated that the minimum change in the THI score to be considered clinically significant is a drop of 6 to 7 points.9 As such, the results of our clinical study suggest that tinnitus and its related symptoms can produce a clinically significant reduction in tinnitus within the first 3 months using the personalized music-based therapy.

An assessment of hyperacusis, a frequent accompaniment of tinnitus,[56] may also be made.[57] The measured parameter is Loudness Discomfort Level (LDL) in dB, the subjective level of acute discomfort at specified frequencies over the frequency range of hearing. This defines a dynamic range between the hearing threshold at that frequency and the loudnes discomfort level. A compressed dynamic range over a particular frequency range is associated with subjectve hyperacusis. Normal hearing threshold is generally defined as 0–20 decibels (dB). Normal loudness discomfort levels are 85–90+ dB, with some authorities citing 100 dB. A dynamic range of 55 dB or less is indicative of hyperacusis.[58][59]
When tinnitus is unexpected and unwelcomed, it can lead to a negative reaction to the tinnitus. This can create a vicious cycle. When tinnitus is perceived, it can prompt emotions, including frustration, fear, unhappiness, etc.  These can, in turn, cause physical reactions such as anxiety and stress.  This reinforces the tinnitus and perpetuates the cycle. 
Exposure to Loud Noise: Exposure to loud or excessive noise can damage or destroy hair cells (cilia) in the inner ear. Because the hair cells cannot be renewed or replaced, this can lead to permanent hearing loss and/or tinnitus. Continued exposure can worsen these conditions, so people who work in loud environments should always wear ear protection. This includes musicians, air traffic controllers, construction workers, military personnel, and first responders. In addition, consider lowering the volume on your iPod and wearing earplugs at loud concerts.
Once the music package (MP3 player preloaded with assigned music tracks and headphones) was ready, participants were briefed on safe listening levels, and were instructed to complete a weekly log book to record their listening duration and frequency. The algorithms which modified the music provided to participants are built into proprietary software that was developed internally by Sound Options Tinnitus Treatments Inc. The modified and placebo music packages consisted of 4 hours of classical music.
Every person living with tinnitus hears a unique sound. The sound can be a low or high frequency, and its volume and pitch may change over time, with the severity varying from person to person. Those with acute tinnitus may struggle to sleep, focus at work, or communicate with others. In such cases, treatment plays a crucial role in helping an individual regain control of his or her life.

As of 2014 there were no medications effective for idiopathic tinnitus.[3][73] There is not enough evidence to determine if antidepressants[81] or acamprosate are useful.[82] While there is tentative evidence for benzodiazepines, it is insufficient to support usage.[3] Usefulness of melatonin, as of 2015, is unclear.[83] It is unclear if anticonvulsants are useful for treating tinnitus.[3][84] Steroid injections into the middle ear also do not seem to be effective.[85][86]
This study has several strengths. It included a relatively large number of patients, reducing the possibility of bias by “masking” which treatment patients received, classifying participants according to the severity of their tinnitus and using highly standardised interventions. Also, the researchers used established scales to measure the severity of tinnitus and its impact on quality of life.
Changing Prescriptions, OTC Medications and Food Additives. Sometimes the cause of tinnitus is a prescription (such as an antibiotic), an over the counter medication or a food additive. As an example, two very common prescriptions that have been shown to cause tinnitus are quinine and chloroquine, which are both used to prevent malaria. Certain diuretics and cancer medications can also cause tinnitus. Even something as simple as OTC aspirin can generate tinnitus in some people. The food additives NutraSweet, Splenda and Aspartame have all been linked to tinnitus, and a whole host of other side effects, in clinical studies. These man-made food additives should be eliminated from your diet completely. If any of your medications are causing your tinnitus, your doctor may recommend stopping, reducing or switching them out for other medicines to see if that helps cure your tinnitus.
Research regarding using cognitive behavioral therapy for tinnitus shows that tolerance to tinnitus can be facilitated by “reducing levels of autonomic nervous system arousal, changing the emotional meaning of the tinnitus, and reducing other stresses.” (6) It’s been found that there’s some overlap in anxiety and tinnitus due to an association between subcortical brain networks involved in hearing sounds, attention, distress and memory functions.

When a medication is ototoxic, it has a toxic effect on the ear or its nerve supply. In damaging the ear, these drugs can cause side effects like tinnitus, hearing loss, or a balance disorder. Depending on the medication and dosage, the effects of ototoxic medications can be temporary or permanent. More than 200 prescription and over-the-counter medicines are known to be ototoxic, including the following:
Assessment of psychological processes related to tinnitus involves measurement of tinnitus severity and distress (i.e., nature and extent of tinnitus-related problems), measured subjectively by validated self-report tinnitus questionnaires.[18] These questionnaires measure the degree of psychological distress and handicap associated with tinnitus, including effects on hearing, lifestyle, health and emotional functioning.[62][63][64] A broader assessment of general functioning, such as levels of anxiety, depression, stress, life stressors and sleep difficulties, is also important in the assessment of tinnitus due to higher risk of negative well-being across these areas, which may be affected by or exacerbate the tinnitus symptoms for the individual.[65] Overall, current assessment measures are aimed to identify individual levels of distress and interference, coping responses and perceptions of tinnitus in order to inform treatment and monitor progress. However, wide variability, inconsistencies and lack of consensus regarding assessment methodology are evidenced in the literature, limiting comparison of treatment effectiveness.[66] Developed to guide diagnosis or classify severity, most tinnitus questionnaires have been shown to be treatment-sensitive outcome measures.[67]
Homeopathy, hypnosis, meditation and acupuncture are also thought to suppress tinnitus conditions. Studies have shown acupuncture can help relieve symptoms of tinnitus, but relief may not be seen until you have completed 10 to 15 sessions. Homeopathy, which uses plant, mineral and animal material in doses to help relieve ailments, can also be used as a treatment.  Some remedies can be used to suppress loud roaring noises, echoing, dull humming and other tinnitus symptoms.
The patients were assessed at the start of the study for their hearing ability and the severity of their tinnitus. The researchers assessed the degree of severity using established questionnaires, which looked at health-related quality of life, the psychological distress associated with tinnitus and how far it impaired their functioning. Using this information, researchers divided participants into four groups ranked on the severity of their condition.
An assessment of hyperacusis, a frequent accompaniment of tinnitus,[56] may also be made.[57] The measured parameter is Loudness Discomfort Level (LDL) in dB, the subjective level of acute discomfort at specified frequencies over the frequency range of hearing. This defines a dynamic range between the hearing threshold at that frequency and the loudnes discomfort level. A compressed dynamic range over a particular frequency range is associated with subjectve hyperacusis. Normal hearing threshold is generally defined as 0–20 decibels (dB). Normal loudness discomfort levels are 85–90+ dB, with some authorities citing 100 dB. A dynamic range of 55 dB or less is indicative of hyperacusis.[58][59]
Loud noise is the leading cause of damage to the inner ear. Most patients with noise trauma describe a whistling tinnitus (Nicholas-Puel et al,. 2002). In a large study of tinnitus, avoidance of occupational noise was one of two factors most important in preventing tinnitus (Sindhusake et al. 2003). The other important factor was the rapidity of treating ear infections.
Tinnitus can be perceived in one or both ears or in the head. It is the description of a noise inside a person’s head in the absence of auditory stimulation. The noise can be described in many different ways. It is usually described as a ringing noise but, in some patients, it takes the form of a high-pitched whining, electric buzzing, hissing, humming, tinging or whistling sound or as ticking, clicking, roaring, "crickets" or "tree frogs" or "locusts (cicadas)", tunes, songs, beeping, sizzling, sounds that slightly resemble human voices or even a pure steady tone like that heard during a hearing test.[4] It has also been described as a "whooshing" sound because of acute muscle spasms, as of wind or waves.[7][not in citation given] Tinnitus can be intermittent or continuous: in the latter case, it can be the cause of great distress. In some individuals, the intensity can be changed by shoulder, head, tongue, jaw or eye movements.[8] Most people with tinnitus have some degree of hearing loss.[9]
As of 2014 there were no medications effective for idiopathic tinnitus.[3][73] There is not enough evidence to determine if antidepressants[81] or acamprosate are useful.[82] While there is tentative evidence for benzodiazepines, it is insufficient to support usage.[3] Usefulness of melatonin, as of 2015, is unclear.[83] It is unclear if anticonvulsants are useful for treating tinnitus.[3][84] Steroid injections into the middle ear also do not seem to be effective.[85][86]

Individuals were recruited from within and around Hamilton, Ontario via online announcements and audiology clinics. Applicants were initially interviewed via telephone to screen for all inclusion and exclusion criteria for the study in order to determine whether they qualified for on-site screening. The on-site screening, and characterization of participants’ hearing thresholds and tinnitus profiles were conducted in a lab at McMaster University using a computer-based tinnitus assessment tool. Participants were randomly allocated to the treatment or placebo-control group. The assignment of the treatment or placebo music package was completed by a distributor site independent of the research study site. Participants and research personnel were blinded to which music package the participants received.

If you’re struggling with tinnitus and experience anxiety or depression relating to your condition, cognitive behavioural therapy is a form of counselling that helps you to cope and readjust your negative feelings. Tinnitus retraining therapy (TRT) can also be used in conjunction with CBT, harnessing the body's natural ability to tune out sounds and make it part of your subconscious mind rather than at the forefront.
Cochlear Implants. These implants are a treatment option for patients that have a severe hearing loss along with tinnitus. Cochlear implants are designed to bypass any damaged parts of the inner ear and send the electrical signals sound makes directly to the auditory nerve. By bringing in outside noise, these implants can effectively mask your tinnitus, as well as stimulate your neural circuits to change.
Tinnitus that's continuous, steady, and high-pitched (the most common type) generally indicates a problem in the auditory system and requires hearing tests conducted by an audiologist. Pulsatile tinnitus calls for a medical evaluation, especially if the noise is frequent or constant. MRI or CT imaging may be needed to check for a tumor or blood vessel abnormality.
×